Meanwhile, high-risk samples were also categorized as malignant glioma subtype like IDH wild-type gliomas (Figure 3G), MGMT unmethylated gliomas (Figure 3H), 1p19q non-codel gliomas (Figure 3I), and mesenchymal/classical gliomas (Figure 3J). Here, MGMT is linked to malignant glioma.