SELE and diabetes mellitus: It has to be underlined, however, that in patients with new onset diabetes (N=19), not only sKlotho concentration was significantly lower than in control group (1824.9 ± 1211.4 pg/mL vs. 2790.3 ± 1423.9 pg/mL, p=0.0316), but also sICAM-1 and E-selectin concentrations were higher than in controls (respectively: 299.9 ± 50.5 ng/mL vs. 267.7 ± 75.3 ng/mL, p=0.0303; 54.9 ± 18.5 ng/mL vs. 42.1 ± 17.2 ng/mL, p=0.0316), whereas sVCAM-1 was comparable between those groups (682.9 ± 162.1 ng/mL vs. 616.3 ± 139.8 ng/mL).