Multiple innate and adaptive immune responses such as activation of NLRP3 inflammasomes and Th1/Th17 cell differentiation occur during myocarditis (Yuan et al., 2010; Yu et al., 2013; Tschöpe et al., 2017; Wang et al., 2019; Zarak-Crnkovic et al., 2019). Here, NLRP3 is linked to myocarditis.