Two of these associations were the same index SNPs or proxies thereof reported in the primary PAD analysis near CDKN2BAS-1 and CHRNA3. Rs2107595, an index SNP near HDAC9, was associated with PAD in individuals without diabetes (EAFnodiabetes 0.16; ORnodiabetes [95% CI], 1.16 [1.11–1.21], Pnodiabetes=3.6×10−8) but was not detected in the primary PAD analysis or in individuals with diabetes (Table, Figure 1, Table VI and Figure IV in the Data Supplement). This evidence concerns the gene CHRNA3 and diabetes mellitus.