GADD45A and neoplasm: Growth arrest and DNA damage-inducing protein 45 (Gadd45) family members, including Gadd45a, Gadd45b, and Gadd45g, have been implicated in many basic processes, such as DNA repair [16], genome stability [17], epigenetic regulation [18], cell cycle arrest [19], apoptosis [20], tumor development [21], and embryogenesis [22].