The tumor 3 (pT3N0M0, stage IIA, 60% tumor content) harbored ERBB2 amplification (CN = 3.0), APC p.S1400*(AF = 40.52%), APC p.R302*(AF = 17.90%), PIK3CA p.E542K(AF = 21.72%) and TP53 p.A159V(AF = 58.79%). The gene discussed is ERBB2; the disease is neoplasm.