TARDBP and neurodegenerative disease: Although TDP-43 became widely known as a protein involved in the pathology of a number of neurodegenerative diseases following the publication by Neumann et al., in 2006 (11), prior to that, we reported cloning of TDP-43 from a mouse testis complementary DNA (cDNA) library as a transcription factor binding to the promoter of the testis-specific Acrv1 gene (12).