DICER1 and mesenchymal hamartoma: The association of DICER1 mutation with hepatic manifestations was reported in two cases of “mesenchymal hamartoma” of the liver (MHL) in 26-month-old and 75-month-old boys; both children had heterozygous pathogenic DICER1 variants and an accompanying somatic hot-spot RNase IIIb DICER1 mutation, in one case, and a heterozygous in-frame germline deletion in the other, but a somatic mutation was not seen105.