Overall, 95 genes appear significant in case of head and neck cancer and STC2, PGK1, P4HA1, HK1, SPIB, ANXA5, SERPINE1, HGF, PFKM, TGFB1, L1CAM, ELK4, EHF, and CDK2 appear to be highly significant which have p-values even lower than or equal to 0.0013. The gene discussed is SPIB; the disease is head and neck cancer.