Remarkably, other laboratories have also shown that genetic inactivation of NUPR1 stops the growth of HCC [19], non-small cell lung cancer [20], cholangiocarcinoma [21], glioblastoma [22], multiple myeloma [23], osteosarcoma [24], and more recently ovarian [25] and gastric cancer [26]. Here, NUPR1 is linked to hepatocellular carcinoma.