FKBP5 and nonpapillary renal cell carcinoma: Immunohistochemistry (IHC) staining of FKBP51 in 70 ccRCC samples and 49 adjacent normal tissues showed that the protein levels of FKBP51 were significantly higher in ccRCC tissues than in adjacent nontumorous tissues (ANTs) (p < 0.001, Fig. 1d, e), and upregulated in patients who developed distant metastasis compared to patients without distant metastasis (p < 0.05, Fig. 1f and Table 1).