RIGI and breast cancer: However, the fibroblasts in BC can deploy these unshielded RN7SL1 proteins in exosomes through the activated Notch-Myc pathway induced by the tumor cells, and this unshielded RN7SL1 can induce an inflammatory response through activated RIG-I that is transported to immune cells and can promote the growth and invasion of tumors when it is transported to BC cells [8] (Fig. 3).