EPHA2 and neoplasm: In brief, C134 had no antitumor effect in this resistant tumor model, consistent with our previous studies.40 In contrast, treatment with the C134-based EphA2 expressing virus (C170) signficanctly reduced tumor growth in comparison to C134 treatment (C170 (n=7) vs C134 (n=8), p=0.0021; C170 (n=7) vs saline (n=6), p<0.0001; figure 7E; C170 (n=7) vs C134 (n=10), p=0.0011; adjusted p value by pairwise analysis (Tukey-Kramer); figure 7F).