ITGAE and neoplasm: Of note, activation of tumor DCs, especially CD103+ cDC1s, is critically important for initiating the tumor-infiltrating CTL responses by cross-presenting acquired tumor antigens.26–28 Nonetheless, DCs represent a rare tumor population because tissue-resident CD103+ DCs fail to accumulate in injured tissue.29 In our study, rlipoE7m-MoGM therapy induced a broad immune response involving multiple myeloid cell types, such as DCs and macrophages.