BAP1 mutations are frequent in MPM (23–67%) and in other tumor types, including uveal melanoma (31–50%), cholangiocarcinoma (20–25%), and clear cell renal cell carcinoma (CCRCC) (8–14%) (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19). The gene discussed is BAP1; the disease is neoplasm.