The use of EM Bokashi® preparation in the diet of pregnant sows caused an increase in the percentage of the subpopulations of B cells with CD19+, CD21+ and CD5+CD19+ expression in the colostrum and milk, which demonstrates an increase concentrations of immunocompetent cells and indicates stimulation of humoral immune mechanisms that protect the sow and the piglets against infections by producing activated B cells and synthesizing antibodies. This evidence concerns the gene CR2 and infection.