AGTR1 and congestive heart failure: Stimulatory AT1-AAs may increase inflammatory burden, weakness, and frequency of falls, potentially worsening the condition and increasing mortality.26 In addition, AT1-AAs have been implicated in the pathology of congestive heart failure, leading to worse allograft outcome.32,33 In a previous study,8 AT1-AAs were identified in individuals with normal blood pressure who were followed up for 5 years.