RENBP and laryngotracheoesophageal cleft: Univariate analysis of all 183 study subjects showed that the presence of LC at a base (hazard ratio [HR] 3.248, P < .015) and ≥50% reduction in the qHBs Ag level after 1 year of antiviral therapy (HR 0.085, P < .017) were associated with the occurrence of all critical events.