LMP-1 gene, the major oncogene of EBV was identified in several cases of hepatic IPT-like FDC sarcomas.[1,4] Positive staining of the FDC markers include CD21, CD35, and EBV-encoded small RNAs, while negative expression in CD23, SMA, Desmin, ALK1, and S-100 are in the present case. The gene discussed is DES; the disease is sarcoma.