Additionally, EST1 expression has also been found to promote tumor angiogenesis in many cancers.[34] Further research provided evidence that ETS1 played a part through regulating the expression of HIF-related genes, consistent with the results of GO and KEGG enrichment analyses in our research.[38] However, our research came to the conflicting conclusion that the elevated expression of ETS1 was a protective feature for prognosis. The gene discussed is SULT1E1; the disease is cancer.