There is no obvious research report available related to glioma focusing on G6PC, VGLL2, and HTR2C, from which 2 inferences can possibly be drawn: first, these are not necessarily related to glioma or, second, whether these key targets are related to glioma has not been studied yet, which provides a theoretical reference for further evaluation. The gene discussed is VGLL2; the disease is glioma.