The biomarkers on the surface of the cancer cell membrane, such as T antigen-Galectin-3 and EpCAM, make cancer cells have homologous targeting and immunogenicity (Hainaut & Plymoth, 2013; Li et al., 2017; Tian et al., 2017), which could overcome the environment of immune clearance and nonspecific attachment in vivo. This evidence concerns the gene LGALS3 and cancer.