Thus, we next sought to test whether different ALS‐related RBPs capture distinct ALS‐related information in VCP‐mutant MN cultures by analysing the model performances of ALS classifiers trained with images immunolabelled with antibodies against TDP‐43, FUS, SFPQ, hnRNPK or hnRNPA1 only (hereafter named ALS|RBPs classifiers). Here, SFPQ is linked to amyotrophic lateral sclerosis.