IL6 and coronary artery disorder: While CAD case subgroup did not yield significant association (p = 0.12), IL-6 levels were found to be significantly higher amongst the ‘C’ allele carriers in the CAD free control subgroup (SMD 0.10, 95% CI 0.02–0.17 pg/ml, Z value = 2.62, p = 0.009) as shown in Fig. 4, Panel A and Supplementary Fig. 3.