LIMK1 and Intellectual disability: Additionally, quite recent andunexpected findings (Davis, Zhong, 2017) reveal a new targetof intellectual disabilities: learning acquisition and memory erasure (forgetting) are governed by different signal cascades,correspondently cAMP-dependent and actin remodeling cascadesmall GTPase Rac1 – LIMK1 (the key enzyme of actinremodeling LIM-kinase 1) and its phosphorylation substrateсofilin.