We further assessed the correlation between the expression of the UGT1A gene family and the pathological stage of PC in patients and found a significant correlation between the expression of UGT1A1 (P = 0.00386), UGT1A6 (P = 0.00378), UGT1A10 (P = 0.00244), and pathological stage (Figure 2). Here, UGT1A1 is linked to pachyonychia congenita.