Blood calcium concentration and NSE did not differ between the OM and NM groups; however, compared with the NM group, alkaline phosphatase, hemoglobin, CA-125, CA-199, CA-153, AFP, CEA, CYFRA21-1, and TPSA were significantly higher in the OM group (p < 0.05); detailed results are presented in Table 2. This evidence concerns the gene ENO2 and ocular melanoma.