SLURP-1 expression is down-regulated in primary and metastatic melanomas compared with normal cells (Bergqvist et al., 2018; Arousse et al., 2019), moreover the elevated level of SLURP-1 in plasma correlates with a better survival prognosis for pancreatic cancer patients (Throm et al., 2018). This evidence concerns the gene SLURP1 and pancreatic neoplasm.