BRD2 and amenorrhea: Primary outcome was amenorrhea at 12–24 months after end of chemotherapyAmenorrhea rate chemotherapy alone, 38%Amenorrhea rate chemotherapy plus OFS, 22% (P = 0.015)POF defined as the presence of amenorrhea and elevated FSH (> 25 IU/L)POF rate chemotherapy alone, 34.8%POF rate chemotherapy plus OFS, 18.5%