CYBRD1 levels (Figure 3 and Table 4) were significantly associated with mucopolysaccharidoses (NES = 1.749, NOM P=0.025; FDR, P=0.097) (Figure 3(a)), the butyrophilin BTN family (NES = 1.682; NOM P=0.023; FDR, P=0.095 (Figure 3(b)), the EGFR/SMRTE pathway (NES = 1.670, NOM P=0.025; FDR, P=0.097) (Figure 3(c)), IRF3-mediated induction of type I INF (NES = 1.698, NOM P=0.023; FDR, P=0.095) (Figure 3(d)), FOXO-mediated transcription of cell cycle genes (NES = 1.767, NOM P=0.011; FDR, P=0.078) (Figure 3(e)), and the ERK pathway (NES = 1.766, NOM P=0.008; FDR, P=0.07) (Figure 3(f)). This evidence concerns the gene IRF3 and mucopolysaccharidosis.