Our present bioinformatics analyses revealed that CYBRD1 expression was associated with mucopolysaccharidoses, the butyrophilin BTN family, the EGFR/SMRTE pathway, IRF3-mediated induction of type I INF, FOXO-mediated transcription of cell cycle genes, and the MAPK/ERK signaling pathway, which are related to the proliferation and metastasis of OV cells. The gene discussed is EGFR; the disease is mucopolysaccharidosis.