Intriguingly, in patients with ACC (Figure 9A, p = 0.015), BRCA (Figure 9B, p = 0.032), KICH (Figure 8C, p < 0.001), KIRC (Figure 8D, p < 0.001), KIRP (Figure 8E, p = 0.0029), and LUAD (Figure 9F, p < 0.044), the PIMREG expression were significantly increased stage IV compared with stage I. In addition, the PIMREG expression in stage III was also higher than stage I in BRCA (Figure 9B, p = 0.039), KIRP (Figure 9E, p = 0.0014), LUAD (Figure 9F, p = 0.033), LIHC (Supplementary Figure 3, p = 0.0035) and TGCT (Supplementary Figure 3, p < 0.001). This evidence concerns the gene PIMREG and adrenal cortex carcinoma.