PIMREG and cancer: In particular, the expression of PIMREG positively corresponded to TMB in 22 cancer categories, including ACC, BLCA, BRCA, CHOL, COAD, KICH, KIRC, LGG, LUAD, LUSC, MESO, OV, PAAD, PRAD, SARC, SKCM, STAD, TGCT, THCA, UCEC, and UCS, while negatively correlated with TMB in DLBC, ESCA and THYM (Table 1 and Figure 10A).