CD4 and allergic asthma: In the model of allergic asthma, CD9+ B cells play a role in airway inflammation suppression by inhibiting Th2- and Th17-driven inflammation in an IL-10-dependent manner (3) while MZB cells reduce the CD8 T cell function and IFN-γ+ CD4 T cells during the early stages of Leishmania donovani infection (4).