PRL and sexual dysfunction: Although the exact mechanisms that cause sexual dysfunction remain elusive, it is suggested that the inhibitory effects of serotonergic antidepressants lead to blunted dopamine release in hypothalamic and mesolimbic areas and neuroendocrine imbalance such as elevated prolactin secretion and reduced testosterone level (Lyons et al., 2016; Bijlsma et al., 2014).