This is supported by recent studies confirming the importance of c-MYB in a broad range of AML subtypes (Armenteros-Monterroso et al., 2019; Takao et al., 2021) (REFs–Takao et al. DOI 10.7554/eLife.65905; Armenteros-Monterroso et al. DOI: 10.1038/s41375-019-0495-8). This evidence concerns the gene MYB and acute myeloid leukemia.