MLKL and asthma: In a mouse model of allergic inflammation, Aspergillus fumigatus extract-induced asthma in vivo shows that bioactive IL-33, a proinflammatory cytokine, released during tissue damage to activate basophils and eosinophils is directly induced by necroptosis, which is blocked by GW806742X, a murine MLKL inhibitor (Shlomovitz et al., 2019).