IFNB1 and asthma: In a mouse model of asthma exacerbations induced by in-house dust mite for inflammation and double-stranded RNA for exacerbation, both cell death markers, MLKL phosphorylation and lactate dehydrogenase, were increased and were observed more in IFNβ−/− mice; thus, IFN-β deficiency may be a regulator of necrosis and necroptosis (Cerps et al., 2018).