A regulated process against infection called neutrophil efferocytosis impairment by Klebsiella pneumoniae (KPn) through the activation of necroptosis machinery is restored with RIPK-1 inhibitor Necrostatin (Nec)-1s or RIPK3 inhibitor GSK’872, which improve the overall disease outcome in KPn-infected mice (Jondle et al., 2018). This evidence concerns the gene RIPK3 and infection.