CYP4Z1 is mainly distributed in human liver, kidney, skeletal muscle, testis, and mammary, and is highly expressed in breast cancer, and a regulator of tumor angiogenesis and growth of breast cancer (Yu et al., 2012; Wang et al., 2016; Nunna et al., 2017; Yang et al., 2017). The gene discussed is CYP4Z1; the disease is breast carcinoma.