In inflammatory bowel disease, due to the infiltration of inherent and adaptive immune cells into the lamina propria, the concentration of local proinflammatory cytokines (IL-1β, IL-6, and TNF-α) increases, which affects the immune balance required for normal intestinal homeostasis (Lee and Kim, 2012; Műzes et al., 2012). This evidence concerns the gene TNF and inflammatory bowel disease.