In order to analyze the expression characteristics of 14 genes in tumors as compared to normal tissues, we searched the TCGA database for the expression of these 14 genes in 31 tumors and their normal control tissue (Figure S2), and we found PRMT6, PML, CDK1, FOXM1, SERPINE1, ID2, TP63 and NPM1 was significantly overexpression in GBM (Figure S3). The gene discussed is CDK1; the disease is glioblastoma.