The PON1 rs854560 T allele corresponded with a higher risk of CHD-related death in non-DM men18, an increased risk of CHD in Iranian patients with atherosclerosis41, the higher prevalence of ischemic cerebral stroke in the entire HD population32 and end-stage NIDDM nephropathy individuals27, but not with cardiovascular, cardiac, or vascular mortality in the whole HD subjects32. This evidence concerns the gene PON1 and coronary artery disorder.