TP53 and Insulin resistance: Combined with the results of molecular docking, we can speculate that AM-AS compound may act on key signal pathways such as TNF pathway, insulin resistance pathway, HIF-1 pathway, NF- kappa B pathway, and cAMP pathway through core targets such as TNF, IL-6, VEGFA, TP53, CASP3, JUN, AKT1 and so on.