Treatment with these peptides did not change the inclusion of exon 8 of the CAPZB gene, regulated by CELF128, nor exon 19 of the DLG1 gene, which remains unchanged in DM1 patients29, suggesting a specific effect on the regulatory factors MBNL1 and 2 in the disease (Fig. 1e–g). This evidence concerns the gene DLG1 and myotonic dystrophy type 1.