In tumor and met, the top differential TF footprints are FOSL1JUNB, JUNvar.2, FOSL1JUN, FOSL2JUNB, FOSJUN, FOSJUND, Smad2Smad3, FOSBJUNB, FOSJUNB, JUNB, JUND, FOS, FOSL1JUND, BATF, FOSL2JUND, FOSL2JUN, JUNJUNB, FOSL1, JDP2, BATFJUN, BATF3, and FOSL2 (Fig. 4a). The gene discussed is FOSL2; the disease is neoplasm.