PPARA and metabolic dysfunction-associated steatohepatitis: In the present study, we investigated the comparative effects of saroglitazar (SARO), a dual PPARα/γ agonist, versus fenofibrate (FENO) and pioglitazone (PIO) as separate α and γ agonist on the adipose tissue factors and inflammatory components of NASH, developed in rats using a high-fat formulation.