As shown by the results, miR-105-5p overexpression could effectively cut down the luciferase activity of wild type of RAB22A (RAB22A-WT) but not the mutant type of RAB22A (RAB22A-Mut) in CRC cells compared to NC mimics (Fig. 4H), suggesting the binding ability between RAB22A and miR-105-5p. Here, RAB22A is linked to colorectal carcinoma.