CD8A and familial pancreatic carcinoma: Immune cell analysis showed that IFI27 has a significant effect on the immune cell infiltration of pancreatic cancer, especially CD8+ T cells, which are also named cytotoxic T-lymphocytes (CTL) and are reported to eliminate transformed tumor cells and regulates immune response [35], and the degree of CD8+ T cells infiltration is lower in the high IFI27 group.