PVT1 and osteoarthritis, knee: Recent studies have found that the expression level of PVT1 in chondrocytes of knee osteoarthritis is three times more than that of normal chondrocytes [11], and lncRNA PVT1 can regulate the apoptosis of chondrocytes of osteoarthritis through the adsorption of miR-488-3p, thus affecting the occurrence and development of osteoarthritis [12].