ASCL1 and epilepsy: To this end, we recorded electroencephalographic (EEG) activity in the KA-injected hippocampus 6–8 weeks after injection of the retrovirus encoding Ascl1/Dlx2 or the control retrovirus (Figure 5A), i.e., several weeks after epilepsy development was completed in all mice and had led to the occurrence of recurrent seizures, which is in agreement with our previous studies showing chronic epilepsy in all KA-injected mice in this model (Heinrich et al., 2011b; Riban et al., 2002).