GNAI1 and Dystonia: Similarly, a dystonia model that had 0.5 × [D2R]tot and 2.0 × [RGS]tot (Fig 6A, red circle) showed high ACbasal and weak responses to the DA dips (Fig 6E; ACbasal = 57% where [Gi-GTP]basal = 0.050 μM; ACdip = 94% where [Gi-GTP]dip = 0.0043 μM).