The authors thank our Mass General Brigham colleagues Tanya Mayadas and Andrew H. Lichtman for advice and helpful discussions; David S. Milstone and Vannessa Davis for assistance with SC sectioning setup and photomicroscopy of SC specimens; Francisco Quintana for his advice on establishing the R-EAE model; Richard Mitchell for his critical review and discussion of the data, histopathology images, and the manuscript; and Sean Stowell for thoughtful discussion of the impact of anti-CD47 Ab Miap410–induced anemia on EAE. This evidence concerns the gene CD47 and anemia (phenotype).