Intriguingly, ANLN has been shown to play a role in the promotion of EMT in lung adenocarcinoma and cell–cell adhesion, migration, and invasion in PC [55, 56], indicating a potential role of ANLN in various stages of the metastatic cascade, including invasion of the basement membrane, intravasation, extravasation, and colonization at secondary sites (Table 2). This evidence concerns the gene ANLN and lung adenocarcinoma.