Decreased survival was significantly associated with the low expression of four DEGs, including secretogranin V (SCG5), crystallin beta A2 (CRYBA2), carboxypeptidase E (CPE), and chromogranin B (CHGB), indicating that the abnormal regulation of these genes in cancer may impact overall survival and the metastatic properties of PC tumors [46] (Table 1). The gene discussed is CRYBA2; the disease is cancer.